By Yakov M Tseytlin
Advanced Mechanical types of DNA Elasticity comprises assurance on 17 various DNA versions and the function of elasticity in organic capabilities with vast references. the radical complex helicoidal version defined displays the direct connection among the molecule helix constitution and its particular homes, together with nonlinear good points and transitions. It offers an advent to the nation of the sector of DNA mechanics, identified and familiar types with their brief research, in addition to insurance on experimental tools and knowledge, the impression of electric, magnetic, ionic stipulations at the patience size, and dynamics with viscosity impact. It then addresses the necessity to comprehend the character of the non-linear overstretching transition of DNA below strength and why DNA has a unfavourable twist-stretch coupling.
- Includes insurance of 17 modern types of DNA mechanics with analysis
- Provides comparability of DNA and RNA mechanical features
- Covers advances in experimental ideas together with AFM, X-ray, and optical tweezers
- Contains broad references for extra reading
Read or Download Advanced Mechanical Models of DNA Elasticity PDF
Best bioinformatics books
Bioinformatics, Biocomputing and Perl offers a latest advent to bioinformatics computing talents and perform. Structuring its presentation round 4 major parts of research, this booklet covers the abilities important to the day by day actions of today’s bioinformatician. every one bankruptcy features a sequence of maxims designed to spotlight key issues and there are workouts to complement and cement the brought fabric.
Biophysical versions were utilized in biology for many years, yet they've been restricted in scope and measurement. during this publication, Bernhard Ø. Palsson exhibits how community reconstructions which are in response to genomic and bibliomic information, and take the shape of confirmed stoichiometric matrices, might be switched over into dynamic versions utilizing metabolomic and fluxomic info.
The 2 quantity set LNCS 9043 and 9044 constitutes the refereed lawsuits of the 3rd overseas convention on Bioinformatics and Biomedical Engineering, IWBBIO 2015, held in Granada, Spain in April 2015. The 134 papers awarded have been conscientiously reviewed and chosen from 268 submissions. The scope of the convention spans the subsequent parts: bioinformatics for healthcare and ailments, biomedical engineering, biomedical snapshot research, biomedical sign research, computational genomics, computational proteomics, computational platforms for modelling organic strategies, eHealth, subsequent new release sequencing and series research, quantitative and structures pharmacology, Hidden Markov version (HMM) for organic series modeling, advances in computational intelligence for bioinformatics and biomedicine, instruments for subsequent new release sequencing information research, dynamics networks in approach medication, interdisciplinary puzzles of measurements in organic structures, organic networks, excessive functionality computing in bioinformatics, computational biology and computational chemistry, advances in drug discovery and ambient intelligence for bio emotional computing.
This glorious ebook covers wide-ranging subject matters in interdisciplinary microbiology, addressing numerous learn features and highlighting complex discoveries and techniques. It offers the interesting subject of contemporary biotechnology, together with agricultural microbiology, microalgae biotechnology, bio-energy, bioinformatics and metagenomics, environmental microbiology, enzyme expertise and marine biology.
- Methods in Modern Biophysics
- Advances in Diagnostic and Therapeutic Ultrasound Imaging (Bioinformatics & Biomedical Imaging)
- Microarray Image Analysis: An Algorithmic Approach (Chapman & Hall CRC Computer Science & Data Analysis)
- Minicircle and Miniplasmid DNA Vectors: The Future of Nonviral and Viral Gene Transfer
Additional info for Advanced Mechanical Models of DNA Elasticity
1964. Fundamental equations of the theory of asymmetric elasticity. PMM 28 (3), 401, (in Russian). , 2008. Modeling DNA at the mesoscale: challenge for nonlinear science? Nonlinearity 21, T91–T100. , 2005. Genetics: A Conceptual Approach, second ed. H. Freeman, New York, NY. , 2011. /physics-of-DNA. , 2008. Discovery of DNA structure and function: Watson and Crick. Nat. Edu. , 1999. Sequence-dependent mechanics of single DNA molecules. Nature Struct. Biol. 6 (4), 346–349. , 1998. Diversity of prokaryotic chromosomal proteins and the origin of the nucleosome.
Ising model for B-Z transition in supercoiled DNA. Bul. Math. Biol. 54 (5), 727–732. , 2006. DNA overwinds when stretched. Nature 442, 836. , 1994. HMG domain proteins: architectural elements in the assembly of nucleoprotein structures. Trends Genet. 10 (3), 94–100. , 2006. Investigation of the ssDNA backbone molecule mechanical behavior using atomistic-continuum mechanics method. In: Technical Proceedings of the 2006 NSTI Nanotechnology Conference and Trade Show, vol. 2. pp. 321–324. NSTI-Nanotech (Chapter 4).
The bead positioning software determines the DNA extension ∆LDNA and the particle transverse fluctuations dx. , 2010) through the formula Fmag = kBT ∆LDNA /<δ x 2 >. , 2013) have the ability to resolve particle position to within 1 Å at 100 Hz, and to measure the extension of 1566 bp DNA with 1 nm precision at 100 Hz, in the presence of thermal noise. The requirement for sufficient light at high frames rates is fulfilled with Force Application, Measurement, and Manipulation Accessories Chapter | 2 45 a super luminescent diode (SLD), and replacing the conventional 60 Hz CCD with a high-speed CMOS camera.
Advanced Mechanical Models of DNA Elasticity by Yakov M Tseytlin