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By Rachel Ballard-Barbash, David Berrigan (auth.), Nathan A. Berger (eds.)

ISBN-10: 1441955143

ISBN-13: 9781441955142

ISBN-10: 1441955151

ISBN-13: 9781441955159

Energy stability and melanoma, Epidemiology and review is the 1st in a chain of monographs to handle the a number of aspects of the realm huge pandemic of obese and weight problems and its relation to melanoma. This quantity, authored by way of major specialists of their standpoint fields, presents a wide and accomplished evaluation of the matter from the epidemiologic standpoint with concentrate on either common and targeted populations in addition to an outline of power molecular mechanisms and reports of the newest reviews of things impacting the organization of power stability and melanoma together with the results of genetics, caloric restrict, workout, habit and the equipped environment.

The amassed chapters and the authors contributing to this preliminary quantity signify a transdisciplinary method of learn and enhance novel methods to appreciate and clear up what, in past times, is a globally refractory challenge. The booklet is written to be comprehensible and informative to participants from all involved disciplines. it's going to serve to orient scholars, investigators, nutritionists, public health and wellbeing officers, group planners, clinicians and coverage makers to the level of the matter, its a number of dimensions and strength ways for learn and corrective interventions.

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The higher levels of insulin-like growth factors in men compared with women throughout life may explain some of the excess risk for colorectal cancer among men [130]. Other obesity-related factors implicated in the etiology of several of the cancers are growth factors, adipokines including adiponectin and leptin, cytokines, and other inflammatory factors, altered immune response, and oxidative stress [23, 82, 130]. In general, many of these potential mechanistic risk factors have not been investigated together with obesity in relation to risk of cancer.

Source: Larsson SC and Wolk A. Overweight and obesity and incidence of leukemia: A meta-analysis of cohort studies. Int J Cancer. Vol. 122, No. 6, 2008, 1418–1421. 2 Central Adiposity May Play a Role Few studies have examined the relationship of obesity and pancreatic cancer using measures of abdominal obesity, such as waist circumference or waist-to-hip ratio. Some studies have found an increased risk of pancreatic cancer with waist circumference or waist-to-hip ratio but not with increasing BMI [14, 93].

American Cancer Society (2008). Cancer facts & figures 2008. American Cancer Society, Atlanta. 8. Amling CL (2005). Relationship between obesity and prostate cancer. Curr Opin Urol, 15(3):167–171. 9. Anderson JP, Ross JA, Folsom AR (2004). Anthropometric variables, physical activity, and incidence of ovarian cancer: The Iowa Women’s Health Study. Cancer, 100(7):1515–1521. 10. Ballard-Barbash R, Friedenreich C, Slattery M, Thune I (2006). Obesity and body composition. In: Schottenfeld D, Fraumeni JF, Jr.

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Cancer and Energy Balance, Epidemiology and Overview by Rachel Ballard-Barbash, David Berrigan (auth.), Nathan A. Berger (eds.)

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