By Pasko Rakic M.D., Sc.D. (auth.), Richard A. Thompson M.D., John R. Green M.D., F.A.C.S., Stanley D. Johnsen M.D. (eds.)
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Extra resources for Perinatal Neurology and Neurosurgery
A. Thompson, J. R. Green, and S. D. Johnsen. Copyright © 1985 by Spectrum Publications, Inc. 41 Jan Goddard-Finegold 42 clinical assessment at the time of the scans. At present, evaluation for hemorrhages is usually accomplished by bedside ultrasound examinations [11-15]. Ultrasound scans can be done as early as the first few hours after birth without having to transport the very fragile, often mechanically ventilated immature newborn. One prospective evaluation of premature newborns, in which real-time ultrasound imaging of the brain was used to detect PIVH, revealed hemorrhages in 90% of babies less than 34 weeks gestational age .
Chattha, A. , and Richardson, E. P. Pathogenesis and evolution of periventricular leukomalacia in infancy. Arch Neurol. 27:229-236, 1972. 13. , and Taraka, K. Development of cerebrovascular architecture and its relationship to periventricular leukomalacia. Arch Neurol. 35: 11-16, 1978. 14. , and Herndon, R. M. The fine structure of plaques fibromyeliniques in ulegyria in status marmoratus. Acta Neuropath. 14:304-308, 1970. 15. Malamud, N. Status marmoratus: A form of cerebral palsy following either birth injury or inflammation of the central nervous system.
The fetal and newborn rhesus monkey has been studied extensively because of its similarities to man with respect to the physiology of reproduction and to its neuroanatomy at the time of birth. In addition, the animal's size and neurological maturity allow it to be nursed in a manner similar to that of human infants. Monkey fetuses asphyxiated at birth to the point of apnea and then reanimated by resuscitation exhibit hypotonia, poor coordinated movements, and a loss of postural righting reflexes following the insult .
Perinatal Neurology and Neurosurgery by Pasko Rakic M.D., Sc.D. (auth.), Richard A. Thompson M.D., John R. Green M.D., F.A.C.S., Stanley D. Johnsen M.D. (eds.)