By P. Portegies (auth.), Dr. Juan Artigas, Professor Dr. Gernot Grosse, Professor Dr. Fred Niedobitek (eds.)
Compact and obviously prepared, this ebook information current wisdom of AIDS study within the fields of neurology and ophthalmology.
The event won via scientific specialists via operating with various sufferers is gifted including the specified morphologic result of neuropathology. to explain a number of the illness complexes, morphology takes into consideration all equipment of outcome illustration, together with immunohistochemistry and electron microscopy.
The 4 disciplines pointed out within the subtitle describe all points of the CNS with reference to AIDS, together with clinically major opthalmologic results.
Richly illustrated medical and morphological descriptions enables you to comprehend the generally varied CNS signs in addition to ophthalmic involvement.
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Additional resources for The Central Nervous System in AIDS: Neurology · Radiology · Pathology · Ophthalmology
1990). Olsen et al. (1987, 1988) observed hyperintense white matter lesions in one third and Flowers et al. (1990) in two thirds of all examined AIDS patients. In 50 of these patients clinical examinations and/or brain biopsies revealed no signs of opportunistic or neoplastic causes for these foci. The white matter foci in AIDS patients are frequently attributed to the HIV infection itself (Post et al. 1987). Post et al. (1992) reported on follow-up data obtained from asymptomatic and symptomatic HIV-infected individuals.
The subcortical gray matter (e. , the putamina) can be affected symmetrically (Chrysikopoulos et al. 1991). Holmes et al. (1992) discuss whether central pontine myelinolysis can be induced by HIY. Lang et al. (1992) attribute a giant intracranial aneurysm either to the HIV infection or to the administration of zidovudine in high doses. In a rare case of pediatric AIDS presenting with ptosis, nystagmus, and sixth-nerve palsy, MRI was superior to CT in revealing the brain stem lesions, which at autopsy proved to be HIV-induced necrotizing encephalitis and vasculitis (Raphael et al.
5 months after clinical onset and the initiation of chemotherapy. Such calcifications, however, do not necessarily confirm inactivity or definite healing of an inflammatory process. Especially a persisting contrast enhancement in the area of the former lesion indicates inflammatory activity. Besides focal calcifications and parenchymal defects MRI allows the detection of glial scars. Often it fails to visualize calcifications, especially if the calcified foci are small and surrounded by tissue with high signal intensity (e.
The Central Nervous System in AIDS: Neurology · Radiology · Pathology · Ophthalmology by P. Portegies (auth.), Dr. Juan Artigas, Professor Dr. Gernot Grosse, Professor Dr. Fred Niedobitek (eds.)